Three-dimensional structure of Rubella virus factories (2024)

Three-dimensional structure of Rubella virus factories (1) https://doi.org/10.1016/j.virol.2010.06.043 · Three-dimensional structure of Rubella virus factories (2) Full text

Journal: Virology, 2010, №2, p.579-591

Publisher: Elsevier BV

Authors:

  1. Juan Fontana
  2. Carmen López-Iglesias
  3. Wen-Ping Tzeng
  4. Teryl K. Frey
  5. José J. Fernández
  6. Cristina Risco

Funder Ministry of Science and Innovation of Spain

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Three-dimensional structure of Rubella virus factories (2024)

FAQs

What is the structure of the rubella virus? ›

Rubella virus (RuV) is a member of the Togaviridae family, genus Rubivirus. RuV virions are about 70 nm in diameter and are composed of a positive-strand RNA genome (∼9760 nucleotides), the viral protein C, and a viral envelope containing two viral glycoproteins, E1 and E2 [41].

What is the structure of the envelope of the rubella virus? ›

Rubella virus is an enveloped RNA virus with single-stranded, positive polarity RN A. The virus core contains multiple copies of the capsid (C) protein. The envelope consists of a host-derived lipid bilayer with the membrane proteins, glycoproteins E2 and E1, embedded as spikes.

What is the shape of the rubella virus capsid? ›

Rubella virus, scientific name Rubivirus rubellae, is a member of the genus Rubivirus and belongs to the family of Matonaviridae, whose members commonly have a genome of single-stranded RNA of positive polarity which is enclosed by an icosahedral capsid.

What does the rubella virus look like under a microscope? ›

Under a microscope, the rubella virus particles look like small spheres. The rubella virus is spread through the air by infectious droplets when an infected person coughs, sneezes or touches a surface.

What is the genome structure of rubella? ›

It is composed of a pleomorphic nucleocapsid containing a single-stranded, positive-sense RNA genome with 9,762 nucleotides. The virus contains three structural proteins, two in the envelope (E1 and E2) and one in the core (capsid or C protein) surrounding the RNA.

What is the basic structure of the measles virus? ›

The measles virus is a paramyxovirus of the genus Morbillivirus. It is 120 to 250 nm in diameter, with a genome of single-stranded, negative sense RNA, and is closely related to the rinderpest and canine distemper viruses. Two membrane envelope proteins are important in pathogenesis.

What are the 3 shapes of a capsid? ›

The three basic capsid shapes are icosahedral, helical, and prolate; however, the shape of capsids can vary widely. The capsids are made from capsomeres, or protein subunits.

What are the structural proteins of rubella? ›

The structural components of rubella virus are comprised of three proteins, glycoproteins E1 (58kDa), E2 (42–47kDa), and the capsid protein (31kDa) [5, 6]. The glycoproteins are type I transmembrane proteins [5, 7] that form heterodimers on the virion surface [8].

What is the structure of virus capsid? ›

Helical Capsid Structure. Each virus possesses a protein capsid to protect its nucleic acid genome from the harsh environment. Virus capsids predominantly come in two shapes: helical and icosahedral. The helix (plural: helices) is a spiral shape that curves cylindrically around an axis.

What is the physical description of rubella virus? ›

Rubella virus is a spherical, 40- to 80-nm, positive-sense, single-stranded RNA virus with spike-like, hemagglutinin-containing surface projections. An electron-dense 30 to 35 nm core is surrounded by a lipoprotein envelope.

What is the pattern of rubella? ›

Rubella has a worldwide distribution. It usually occurs in a seasonal pattern (i.e. in temperate zones during the late winter and spring), with epidemics every 5-9 years. However, the extent and periodicity of rubella epidemics is highly variable in both developed and developing countries.

How do you identify rubella? ›

The main symptom of rubella is a spotty rash that starts on the face or behind the ears and spreads to the neck and body. The rash takes 2 to 3 weeks to appear after getting rubella. The rash looks red or pink on white skin. It can be harder to see on brown or black skin, but might feel rough or bumpy.

What is the strand of the rubella virus? ›

Rubella is an enveloped single-stranded RNA virus of 9757 nucleotides in length, which contains two long open reading frames, the 5′ proximal, which encodes nonstructural proteins, and the 3′ proximal, which encodes the structural proteins (capsid, E1, and E2).

Is rubella enveloped or nonenveloped? ›

Rubella virus is an enveloped, positive-stranded RNA virus classified as a Rubivirus in the Matonaviridae family.

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